Being selected in the MLB Draft is a tremendous accomplishment and honor for hardworking, talented and dedicated young athletes. It is also a great source of pride for the 6-4-3 DP Baseball organization when the potential of one of our own is validated with an opportunity to become a professional baseball player.
Since the first 6-4-3 teams were formed in 2007 and over the evolving success of the organization, 6-4-3 has witnessed thirty-five (35) of its players drafted or signed by Major League Baseball clubs. Thirteen (13) former 6-4-3 players are active and playing at this time.
To date, the following 6-4-3 players have earned a selection in the MLB Draft (or have been signed by an MLB club):
| Year | Player | High School | Round | Team |
| 2023 | Ty Floyd, RHP | Rockmart | CB-A | Cincinnati Reds (A) |
| 2023 | Liam Sullivan, LHP | Marist | 13th | Washington Nationals (A) |
| 2023 | Austin Emener, LHP | First Presb. Day | 16th | Colorado Rockies (A) |
| 2022 | Druw Jones, OF | Wesleyan | 1st | Arizona Diamondbacks (A) |
| 2022 | Andrew Jenkins, 1B | Pace Academy | 9th | Detroit Tigers (A) |
| 2021 | Ryan Webb, LHP | Pope | 4th | Cleveland Indians (A) |
| 2021 | Brant Hurter, LHP | Woodstock | 7th | Detroit Tigers (A) |
| 2021 | Fraser Ellard, LHP | Homeschooled | 8th | Chicago White Sox (A) |
| 2021 | Ben Harris, LHP | Milton | 8th | Los Angeles Dodgers (A) |
| 2021 | Tyler Tolve, C/OF | Sprayberry | 17th | Atlanta Braves (A) |
| 2021 | Zach Cable, RHP | River Ridge | FA | Chicago White Sox (A) |
| 2020 | Carson Taylor, C | GAC | 4th | Los Angeles Dodgers (A) |
| 2019 | Davis Vainer, RHP | Riverwood | 21st | Houston Astros |
| 2018 | Kevin Smith, LHP | Dunwoody | 7th | NY Mets |
| 2017 | Drew Waters, OF | Etowah | 2nd | Atlanta Braves (A) |
| 2017 | Sean Guenther, LHP | Marist | 7th | Miami Marlins (A) |
| 2017 | Sam Fuller, RHP | Whitefield Acad. | 14th | Los Angeles Angels of Anaheim |
| 2017 | Jonathan Pryor, OF | Woodward Acad. | 19th | Washington Nationals |
| 2017 | Connor Johnstone, RHP | Roswell | 21st | Atlanta Braves |
| 2017 | Jackson Lourie, RHP | Lovett | 24th | Atlanta Braves |
| 2017 | Charlie Madden, C | Dunwoody | 24th | Boston Red Sox |
| 2017 | Jim Voyles, RHP | Holy Innocents | 38th | St. Louis Cardinals |
| 2016 | Josh Merrigan, OF | Walton | 10th | Texas Rangers |
| 2016 | Matt Rowland, RHP | Pope | 11th | Atlanta Braves |
| 2016 | Grayson Harbin, RHP | Allatoona | 35th | New York Mets |
| 2015 | Stephen Moore, RHP | Walker | 10th | Atlanta Braves *Fulfilling Military Service |
| 2015 | Zach Bowers, C | Harrison | 24th | San Francisco Giants |
| 2015 | Chris Cullen, C | West Forsyth | 38th | Oakland Athletics |
| 2015 | Dylan Kelly, C | Centennial | FA | Arizona Diamondbacks |
| 2014 | Michael Branigan, C | Forsyth Central | 22nd | Arizona Diamondbacks |
| 2013 | Kent Emanuel, LHP | Woodstock | 3rd | Houston Astros (A) |
| 2013 | Jared Breen, SS | Sprayberry | 23rd | Baltimore Orioles |
| 2010 | Mathew Price, RHP | Walker | 8th | Boston Red Sox |
| 2010 | Andrew Smith, RHP | Roswell | 40th | Oakland Athletics |
| 2009 | Derek Thomas, OF | Roswell | 44th | Boston Red Sox |
KEY:
(A)- Denotes Active Status
FA- Free Agent Signee